Thiamine hydrochloride is a white crystalline powder with a faint characteristic yeast / nut odor and a bitter taste. It is used to enhance the flavor of foods, including gravies and broths, and can be used as a functional food supplement to increase vitamin B1 content.

Description

Vitamin B1 is a water-soluble vitamin that is easily destroyed by heat treatment in an alkaline environment.

The phosphorylated form of thiamine – thiamine pyrophosphate – is formed in the human body and is a precursor of enzymes that play an essential role in the metabolism of carbohydrates and, in particular, in the processes of decarboxylation of pyruvic acid, β-keto acids.

Action

Vitamin B1 is necessary for the oxidative decarboxylation of keto acids (pyruvic and lactic), the synthesis of acetylcholine, it participates in carbohydrate metabolism and associated energy, fat, protein, water-salt metabolism, has a regulating effect on trophism and the activity of the nervous system.

With an insufficient intake of thiamine, pyruvic and lactic acids accumulate in the tissues, the synthesis of acetylcholine is disrupted, as a result of which the functions of a number of systems, primarily the nervous, cardiovascular and digestive systems, deteriorate.

Thiamine improves blood circulation and is involved in hematopoiesis.

Thiamine optimizes cognitive activity and brain function. It has positive effects on energy levels, growth, normal appetite, learning ability and is essential for muscle tone in the digestive tract, stomach and heart. Thiamine acts as an antioxidant, protecting the body from the damaging effects of aging, alcohol and tobacco.

Like all B vitamins, thiamine has chelating properties.

Indications

Hypo- and avitaminosis B1 (beriberi).

Thiamine is used for diseases of the cardiovascular system, such as:

circulatory failure
myocarditis,
endoarteritis.

Additional intake of thiamine is also necessary when using diuretic drugs for hypertension, congestive heart failure, because they accelerate its excretion from the body.

Vitamin B1 improves the functioning of the nervous system and reduces pain in various neurological diseases. Shown at:

neuritis,
polyneuritis,
peripheral paralysis,
asthenovegetative syndrome, etc.

In dermatological practice, thiamine is used for dermatoses of neurogenic origin; itching of the skin of various etiologies, pyoderma, eczema, psoriasis.

Thiamine is used to treat organic brain dysfunctions such as organic brain damage syndrome, promoting better brain function in healthy people, enhancing learning and mental performance in general. In addition, supplementation with vitamin B1 can help treat depression and a number of other mental illnesses. There is evidence of a preventive effect of thiamine against Alzheimer’s disease.

The use of vitamin B1 is indicated for the treatment of diseases of the digestive system:

peptic ulcer of the stomach and duodenum,
chronic gastritis, accompanied by impaired motor and secretory functions of the stomach,
chronic enteritis with malabsorption syndrome (celiac disease, Whipple’s disease, Crohn’s disease, radiation enteritis),
enterocolitis,
hepatitis,
chronic pancreatitis with secretory insufficiency,
diseases of the operated stomach,
cirrhosis of the liver.

Metabolic disorders and diseases of the endocrine system (thyrotoxicosis, diabetes mellitus, obesity) are also indications for taking thiamine.

Vitamin B1 acts as an antioxidant, protecting the body from the damaging effects of aging, alcohol and tobacco.

It is advisable to use thiamine in industrial contact with carbon disulfide, tetraethyl lead, when working in hot shops.