L-carnitine is a natural substance related to B vitamins. It is a cofactor of metabolic processes that maintain the activity of coenzyme A. Decreases basal metabolism, slows down the breakdown of protein and carbohydrate molecules. Promotes the penetration of mitochondrial membranes and the breakdown of long-chain fatty acids with the formation of acetyl-CoA (necessary to ensure the activity of pyruvate carboxylase in the process of gluconeogenesis, the formation of ketone bodies, the synthesis of choline and its esters, oxidative phosphorylation and the formation of ATP).
Mobilizes fat (the presence of 3 labile methyl groups) from fat depots. Competitively displacing glucose, it includes a fatty acid metabolic shunt, the activity of which is not limited by oxygen (unlike aerobic glycolysis), and therefore the drug is effective in conditions of acute hypoxia (including the brain) and other critical conditions.
It has a neurotrophic effect, inhibits apoptosis, limits the affected area and restores the structure of the nervous tissue. Normalizes protein and fat metabolism, increased basal metabolism in thyrotoxicosis (being a partial antagonist of thyroxine). Restores the alkaline reserve of the blood.
Reduces the formation of keto acids, increases tissue resistance to the influence of toxic decay products, activates anaerobic glycolysis, stimulates and accelerates reparative processes.
Increases the threshold of resistance to physical activity, reduces the degree of lactic acidosis and restores working capacity after prolonged physical exertion. At the same time, it contributes to the economical consumption of glycogen and an increase in its reserves in the liver and muscles.
Does not affect the blood coagulation system.
The daily dose is 0.5-1 g.